A Printed Organic Amplification System for Wearable Potentiometric Electrochemical Sensors.

ABSTRACT: Electrochemical sensor systems with integrated amplifier circuits play an important role in measuring physiological signals via in situ human perspiration analysis. Signal processing circuitry based on organic thin-film transistors (OTFTs) have significant potential in realizing wearable sensor devices due to their superior mechanical flexibility and biocompatibility. Here, we demonstrate a novel potentiometric electrochemical sensing system comprised of a potassium ion (K+) sensor and amplifier circuits employing OTFT-based pseudo-CMOS inverters, which have a highly controllable switching voltage and closed-loop gain. The ion concentration sensitivity of the fabricated K+ sensor was 34?mV/dec, which was amplified to 160?mV/dec (by a factor of 4.6) with high linearity. The developed system is expected to help further the realization of ultra-thin and flexible wearable sensor devices for healthcare applications.

SUBMITTER: Shiwaku R 

PROVIDER: S-EPMC5834464 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature