Ontology highlight
ABSTRACT:
SUBMITTER: Matsueda S
PROVIDER: S-EPMC5834778 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Matsueda Satoko S Itoh Kyogo K Shichijo Shigeki S
Cancer science 20180228 3
Although humoral responses against CTL epitope peptides from lymphocyte-specific protein tyrosine kinase (Lck) antigen have been observed in the majority of healthy donors and cancer patients, the biological activity of the antibody has not been determined. We investigated the biological activity of mAb against CTL epitope peptide of Lck antigen at positions 486-494 (anti-Lck-486 mAb). This mAb induced dendritic cell maturation from murine bone marrow cells by the immune complex form in vitro, a ...[more]