Ontology highlight
ABSTRACT:
SUBMITTER: Eng L
PROVIDER: S-EPMC5835214 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Eng Lars L Garcia Brandon L BL Geisbrecht Brian V BV Hanning Anders A
Biochemical and biophysical research communications 20180207 1
Surface plasmon resonance (SPR) is a well-established method for biomolecular interaction studies. SPR monitors the binding of molecules to a solid surface, embodied as refractive index changes close to the surface. One limitation of conventional SPR is the universal nature of the detection that results in an inability to qualitatively discriminate between different binding species. Furthermore, it is impossible to directly discriminate two species simultaneously binding to different sites on a ...[more]