Ontology highlight
ABSTRACT:
SUBMITTER: Ryu E
PROVIDER: S-EPMC5836158 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Ryu Euijung E Nassan Malik M Jenkins Gregory D GD Armasu Sebastian M SM Andreazza Ana A McElroy Susan L SL Vawter Marquis P MP Frye Mark A MA Biernacka Joanna M JM
Molecular neuropsychiatry 20171028 3
Mitochondrial DNA mutations have been reported to be associated with bipolar disorder (BD). In this study, we performed genome-wide analyses to assess mitochondrial single-nucleotide polymorphism (mtSNP) effects on BD risk and early-onset BD (EOBD) among BD patients, focusing on interaction effects between nuclear SNPs (nSNPs) and mtSNPs. Common nSNP and mtSNP data from European American BD cases (<i>n</i> = 1,001) and controls (<i>n</i> = 1,034) from the Genetic Association Information Network ...[more]