Ontology highlight
ABSTRACT:
SUBMITTER: Cho HS
PROVIDER: S-EPMC5836763 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
The Journal of veterinary medical science 20171218 2
Nervous necrosis virus (NNV), also known as betanodavirus, has been recently implicated in mass mortalities of cultured marine fish. An effective vaccine is urgently needed to protect fish against this virus. However, parenteral immunization methods are very stressful. Individual immunization for thousands of fish is very labor intensive and expensive. Therefore, we expressed NNV coat protein in tobacco chloroplasts and used it as an oral vaccine to induce immunities in fish followed by challeng ...[more]