Pilot Metabolome-Wide Association Study of Benzo(a)pyrene in Serum From Military Personnel.
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ABSTRACT:
SUBMITTER: Walker DI
PROVIDER: S-EPMC5837056 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Publications
Pilot Metabolome-Wide Association Study of Benzo(a)pyrene in Serum From Military Personnel.
Walker Douglas I DI Pennell Kurt D KD Uppal Karan K Xia Xiaoyan X Hopke Philip K PK Utell Mark J MJ Phipps Richard P RP Sime Patricia J PJ Rohrbeck Patricia P Mallon Col Timothy M CT Jones Dean P DP
Journal of occupational and environmental medicine 20160801 8 Suppl 1
<h4>Objective</h4>A pilot study was conducted to test the feasibility of using Department of Defense Serum Repository (DoDSR) samples to study health and exposure-related effects.<h4>Methods</h4>Thirty unidentified human serum samples were obtained from the DoDSR and analyzed for normal serum metabolites with high-resolution mass spectrometry and serum levels of free benzo(a)pyrene (BaP) by gas chromatography-mass spectrometry. Metabolic associations with BaP were determined using a metabolome-w ...[more]
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