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ABSTRACT: Aims
Previous studies have identified sex disparities in the use of cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillators (ICD), although the basis of underutilization in women remains poorly understood. The aim of this study was to assess sex differences in patterns of CRT use with our without ICD.Methods and results
In this cross-sectional study using the National Inpatient Sample database we identified 311 009 patients undergoing CRT implantation in the United States between 2006 and 2012. Demographic and clinical characteristics were compared between men and women undergoing CRT implantation, with special attention to clinical predictors of left ventricular reverse remodelling (CRT response, score range: 0-4) and reduced ICD efficacy (score range: 0-7). When compared to men, women undergoing CRT implantation were significantly more likely to have???3 predictors of CRT response (47.3 vs. 33.2%, P?ConclusionIn this large, contemporary cohort, sex differences in CRT-D implantation were inversely related to predicted CRT efficacy and have increased over time. Future efforts to narrow the gap in CRT-D implantation in men and women may help better align device selection with those most likely to benefit.
SUBMITTER: Chatterjee NA
PROVIDER: S-EPMC5837710 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Chatterjee Neal A NA Borgquist Rasmus R Chang Yuchiao Y Lewey Jennifer J Jackson Vicki A VA Singh Jagmeet P JP Metlay Joshua P JP Lindvall Charlotta C
European heart journal 20170501 19
<h4>Aims</h4>Previous studies have identified sex disparities in the use of cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillators (ICD), although the basis of underutilization in women remains poorly understood. The aim of this study was to assess sex differences in patterns of CRT use with our without ICD.<h4>Methods and results</h4>In this cross-sectional study using the National Inpatient Sample database we identified 311 009 patients undergoing CRT implantation ...[more]