New and old agents in the management of diabetic nephropathy.
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ABSTRACT:
SUBMITTER: Lytvyn Y
PROVIDER: S-EPMC5841607 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Publications
New and old agents in the management of diabetic nephropathy.
Lytvyn Yuliya Y Bjornstad Petter P Pun Nicole N Cherney David Z I DZ
Current opinion in nephrology and hypertension 20160501 3
<h4>Purpose of review</h4>Diabetic nephropathy is a long-standing complication of diabetes mellitus and is responsible for more than 40% of end-stage renal disease cases in developed countries. Unfortunately, conventional renin-angiotensin-aldosterone system (RAAS) inhibitor medications only partially protect against the development and progression of diabetic nephropathy. Moreover, RAAS inhibitors have failed as primary prevention therapy in type 1 diabetes. Thus, agents targeting alternative p ...[more]
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