Ontology highlight
ABSTRACT:
SUBMITTER: Yang F
PROVIDER: S-EPMC5844731 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Yang Fan F Wu Qingjian Q Zhang Yan Y Xiong Haojun H Li Xinzhe X Li Bo B Xie Wei W Zhang Le L Xu Min M Zhang Kebin K He Fengtian F
Oncotarget 20180108 15
Renal cell carcinoma (RCC) is the most common kidney malignancy with poor prognosis. Recently, long noncoding RNAs (lncRNAs) have been demonstrated as important regulators in multiple cancers including RCC. LOC653786 is a lncRNA, but its role in cancer remains unclear. In this study, we for the first time found that LOC653786 was upregulated in RCC tissues and cell lines, and this lncRNA promoted growth and cell cycle progression of RCC cells. Moreover, we showed that LOC653786 elevated the expr ...[more]