Ontology highlight
ABSTRACT:
SUBMITTER: Kim HY
PROVIDER: S-EPMC5846720 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Kim Hye-Yeong HY Wang Xiaolei X Kang Rui R Tang Daolin D Boone Brian A BA Zeh Herbert J HJ Lotze Michael T MT Edwards W Barry WB
PloS one 20180312 3
Noninvasive detection of both early pancreatic neoplasia and metastases could enhance strategies to improve patient survival in this disease that is notorious for an extremely poor prognosis. There are almost no identifiable targets for non-invasive diagnosis by positron emission tomography (PET) for patients with pancreatic ductal adenocarcinoma (PDAC). Over-expression of the receptor for advanced glycation end products (RAGE) is found on the cell surface of both pre-neoplastic lesions and inva ...[more]