Ontology highlight
ABSTRACT:
SUBMITTER: Zacchetti B
PROVIDER: S-EPMC5848461 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Zacchetti Boris B Andrianos Agathoklis A van Dissel Dino D de Ruiter Evelien E van Wezel Gilles P GP Claessen Dennis D
BMC biotechnology 20180312 1
<h4>Background</h4>Filamentous bacteria of the genus Streptomyces produce a large arsenal of industrially relevant antibiotics and enzymes. The industrial production of these molecules occurs in large fermenters, where many streptomycetes form dense mycelial networks called pellets. Pellets are characterized by slow growth and inefficient nutrient transfer and therefore regarded as undesirable from the perspective of productivity. Although non-pelleting strains have increased growth rates, their ...[more]