Ontology highlight
ABSTRACT:
SUBMITTER: Li SS
PROVIDER: S-EPMC5848793 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Li Shan-Shan SS Guan Qi-Yuan QY Zheng Mengmeng M Wang Yu-Qi YQ Ye Deju D Kang Bin B Xu Jing-Juan JJ Chen Hong-Yuan HY
Chemical science 20170829 11
Intracellular biothiols mediate many important physiological and pathological processes. Due to their low content and competing thiol-reactivity, it is still an unmet challenge to quantify them within a complicated intracellular environment. Herein, we demonstrated a strategy to discriminate three biothiols, <i>i.e.</i> cysteine (Cys), homo-cysteine (Hcy) and glutathione (GSH), and quantify their concentrations within single living cells, using one platform of Raman probe. By monitoring the reac ...[more]