Ontology highlight
ABSTRACT:
SUBMITTER: Ganzer PD
PROVIDER: S-EPMC5849415 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
eLife 20180313
Recovery from serious neurological injury requires substantial rewiring of neural circuits. Precisely-timed electrical stimulation could be used to restore corrective feedback mechanisms and promote adaptive plasticity after neurological insult, such as spinal cord injury (SCI) or stroke. This study provides the first evidence that closed-loop vagus nerve stimulation (CLV) based on the synaptic eligibility trace leads to dramatic recovery from the most common forms of SCI. The addition of CLV to ...[more]