Ontology highlight
ABSTRACT:
SUBMITTER: Kathe C
PROVIDER: S-EPMC7612390 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Kathe Claudia C Michoud Frédéric F Schönle Philipp P Rowald Andreas A Brun Noé N Ravier Jimmy J Furfaro Ivan I Paggi Valentina V Kim Kyungjin K Soloukey Sadaf S Asboth Leonie L Hutson Thomas H TH Jelescu Ileana I Philippides Antoine A Alwahab Noaf N Gandar Jérôme J Huber Daniel D De Zeeuw Chris I CI Barraud Quentin Q Huang Qiuting Q Lacour Stéphanie P SP Courtine Grégoire G
Nature biotechnology 20210927 2
Optoelectronic systems can exert precise control over targeted neurons and pathways throughout the brain in untethered animals, but similar technologies for the spinal cord are not well established. In the present study, we describe a system for ultrafast, wireless, closed-loop manipulation of targeted neurons and pathways across the entire dorsoventral spinal cord in untethered mice. We developed a soft stretchable carrier, integrating microscale light-emitting diodes (micro-LEDs), that conform ...[more]