MiRNAs at the Crossroads between Innate Immunity and Cancer: Focus on Macrophages.
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ABSTRACT:
SUBMITTER: Curtale G
PROVIDER: S-EPMC5850100 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Publications
MiRNAs at the Crossroads between Innate Immunity and Cancer: Focus on Macrophages.
Cells 20180208 2
Innate immune cells form an integrative component of the tumor microenvironment (TME), which can control or prevent tumor initiation and progression, due to the simultaneous processing of both anti- and pro-growth signals. This decision-making process is a consequence of gene expression changes, which are in part dependent on post-transcriptional regulatory mechanisms. In this context, microRNAs have been shown to regulate both recruitment and activation of specific tumor-associated immune cells ...[more]
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