Ontology highlight
ABSTRACT:
SUBMITTER: Ou GJ
PROVIDER: S-EPMC5853077 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Ou Guo-Jin GJ Su Pin-Can PC Yu Hao H Ji Xin X Liu Fan F Wang Sheng-Lan SL Kong Yu-Jie YJ Li Ling L Wang Jue J Liu Zhong Z Flegel Willy Albert WA
Journal of translational medicine 20180314 1
<h4>Background</h4>Human neutrophil antigen 3 (HNA-3) is encoded by the SLC44A2 gene. Antibodies against HNAs can cause severe, often fatal, transfusion reactions, known as transfusion-related acute lung injury, and neonatal neutropenia. We explored the 2 common HNA-3 variants in 9 ethnic populations residing in Sichuan and Yunnan provinces of China as compared to the Han population.<h4>Methods</h4>We genotyped for SLC44A2 (rs2288904) by polymerase chain reaction sequence-based typing among bloo ...[more]