Ontology highlight
ABSTRACT:
SUBMITTER: Talal AH
PROVIDER: S-EPMC5853515 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Talal Andrew H AH Dumas Emily O EO Bauer Barbara B Rejman Richard M RM Ocque Andrew A Morse Gene D GD Lucic Danijela D Cloherty Gavin A GA King Jennifer J Zha Jiuhong J Zhang Hongtao H Cohen Daniel E DE Shulman Nancy N Pawlotsky Jean-Michel JM Hézode Christophe C
The Journal of infectious diseases 20180101 3
<h4>Background</h4>It is unknown whether ribavirin (RBV) coadministration modifies the early rate of decline of hepatitis C virus (HCV) RNA in the liver versus plasma compartments, specifically.<h4>Methods</h4>This partially randomized, open-label, phase 2 study enrolled treatment-naive, noncirrhotic patients with HCV genotype 1a. Patients were randomized 1:1 into Arms A and B, and then enrolled in Arm C. Patients received ombitasvir/paritaprevir/ritonavir plus dasabuvir for 12 weeks with either ...[more]