Ontology highlight
ABSTRACT:
SUBMITTER: Deutsch L
PROVIDER: S-EPMC7126165 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Deutsch Liat L Houri Inbal I Ben-Ari Ziv Z Shlomai Amir A Veitsman Ella E Cohen-Ezra Oranit O Issachar Assaf A Mor Orna O Gozlan Yael Y Bruck Rafael R Menachem Yoram Y Zelber-Sagi Shira S Katchman Helena H Shibolet Oren O
BMC infectious diseases 20200403 1
<h4>Background</h4>Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease and hepatocellular carcinoma. Treatment with first generation protease inhibitors (PI) + peg-interferon (pegIFN) and ribavirin (RBV) achieved sustained virologic response (SVR) rates of 65-75% but was associated with multiple side effects. The aim of this study was to evaluate safety and efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir (3D) ± RBV in HCV genotype 1 patients that failed prev ...[more]