Ontology highlight
ABSTRACT:
SUBMITTER: Li D
PROVIDER: S-EPMC5853543 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Li Dapeng D Wang Xuesong X von Schaewen Markus M Tao Wanyin W Zhang Yunfang Y Heller Brigitte B Hrebikova Gabriela G Deng Qiang Q Sun Qiang Q Ploss Alexander A Zhong Jin J Huang Zhong Z
The Journal of infectious diseases 20170601 12
<h4>Background</h4>The global control of hepatitis C virus (HCV) infection remains a great burden, owing to the high prices and potential drug resistance of the new direct-acting antivirals (DAAs), as well as the risk of reinfection in DAA-cured patients. Thus, a prophylactic vaccine for HCV is of great importance. We previously reported that a single recombinant soluble E2 (sE2) vaccine produced in insect cells was able to induce broadly neutralizing antibodies (NAbs) and prevent HCV infection ...[more]