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Monoclonal Antibodies as Prophylactic and Therapeutic Agents Against Chikungunya Virus.


ABSTRACT: Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that is responsible for considerable epidemics worldwide and recently emerged in the Americas in 2013. CHIKV may cause long-lasting arthralgia after acute infection. With currently no licensed vaccines or antivirals, the design of effective therapies to prevent or treat CHIKV infection is of utmost importance and will be facilitated by increased understanding of the dynamics of chikungunya. In this article, monoclonal antibodies against CHIKV as viable prophylactic and therapeutic agents will be discussed.

SUBMITTER: Clayton AM 

PROVIDER: S-EPMC5853615 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature

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Monoclonal Antibodies as Prophylactic and Therapeutic Agents Against Chikungunya Virus.

Clayton April M AM  

The Journal of infectious diseases 20161201 suppl 5


Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that is responsible for considerable epidemics worldwide and recently emerged in the Americas in 2013. CHIKV may cause long-lasting arthralgia after acute infection. With currently no licensed vaccines or antivirals, the design of effective therapies to prevent or treat CHIKV infection is of utmost importance and will be facilitated by increased understanding of the dynamics of chikungunya. In this article, monoclonal antibodies against CH  ...[more]

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