Measles Antibodies in Mother-Infant Dyads in Tianjin, China.

ABSTRACT:

Background

Many measles cases in Tianjin, China, occur in infants whose mothers were born after widespread vaccination programs. We assessed age-specific decreases in maternal measles antibodies in infants and examined maternal and infant characteristics in relation to infant antibody titers.

Methods

Infant and mother dyads were enrolled from a sample of immunization clinics in all Tianjin districts. Participants' antibody titers were measured from dried blood spots. A multivariable log-linear model regressed infant antibody titers onto infant and mother characteristics.

Results

Among 551 infants aged ≤8 months, protective levels of measles antibodies were observed in infants whose mothers had measles titers ≥800 IU/mL (mean antibody titer, 542.5 IU/mL) or 400 to <800

SUBMITTER: Boulton ML 

PROVIDER: S-EPMC5853645 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature