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Acute Effects of Ambient PM2.5 on All-Cause and Cause-Specific Emergency Ambulance Dispatches in Japan.


ABSTRACT: Short-term health effects of ambient PM2.5 have been established with numerous studies, but evidence in Asian countries is limited. This study aimed to investigate the short-term effects of PM2.5 on acute health outcomes, particularly all-cause, cardiovascular, respiratory, cerebrovascular and neuropsychological outcomes. We utilized daily emergency ambulance dispatches (EAD) data from eight Japanese cities (2007-2011). Statistical analyses included two stages: (1) City-level generalized linear model with Poisson distribution; (2) Random-effects meta-analysis in pooling city-specific effect estimates. Lag patterns were explored using (1) unconstrained-distributed lags (lag 0 to lag 7) and (2) average lags (lag: 0-1, 0-3, 0-5, 0-7). In all-cause EAD, significant increases were observed in both shorter lag (lag 0: 1.24% (95% CI: 0.92, 1.56)) and average lag 0-1 (0.64% (95% CI: 0.23, 1.06)). Increases of 1.88% and 1.48% in respiratory and neuropsychological EAD outcomes, respectively, were observed at lag 0 per 10 µg/m³ increase in PM2.5. While respiratory outcomes demonstrated significant average effects, no significant effect was observed for cardiovascular outcomes. Meanwhile, an inverse association was observed in cerebrovascular outcomes. In this study, we observed that effects of PM2.5 on all-cause, respiratory and neuropsychological EAD were acute, with average effects not exceeding 3 days prior to EAD onset.

SUBMITTER: Phung VLH 

PROVIDER: S-EPMC5858376 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

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Acute Effects of Ambient PM<sub>2.5</sub> on All-Cause and Cause-Specific Emergency Ambulance Dispatches in Japan.

Phung Vera Ling Hui VLH   Ueda Kayo K   Kasaoka Shunji S   Seposo Xerxes X   Tasmin Saira S   Yonemochi Shinichi S   Phosri Arthit A   Honda Akiko A   Takano Hirohisa H   Michikawa Takehiro T   Nitta Hiroshi H  

International journal of environmental research and public health 20180209 2


Short-term health effects of ambient PM<sub>2.5</sub> have been established with numerous studies, but evidence in Asian countries is limited. This study aimed to investigate the short-term effects of PM<sub>2.5</sub> on acute health outcomes, particularly all-cause, cardiovascular, respiratory, cerebrovascular and neuropsychological outcomes. We utilized daily emergency ambulance dispatches (EAD) data from eight Japanese cities (2007-2011). Statistical analyses included two stages: (1) City-lev  ...[more]

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