Ontology highlight
ABSTRACT:
SUBMITTER: Thekkeparambil Chandrabose S
PROVIDER: S-EPMC5859503 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Thekkeparambil Chandrabose Srijaya S Sriram Sandhya S Subramanian Subha S Cheng Shanshan S Ong Wee Kiat WK Rozen Steve S Kasim Noor Hayaty Abu NHA Sugii Shigeki S
Stem cell research & therapy 20180320 1
<h4>Background</h4>While a shift towards non-viral and animal component-free methods of generating induced pluripotent stem (iPS) cells is preferred for safer clinical applications, there is still a shortage of reliable cell sources and protocols for efficient reprogramming.<h4>Methods</h4>Here, we show a robust episomal and xeno-free reprogramming strategy for human iPS generation from dental pulp stem cells (DPSCs) which renders good efficiency (0.19%) over a short time frame (13-18 days).<h4> ...[more]