Ontology highlight
ABSTRACT:
SUBMITTER: Peng H
PROVIDER: S-EPMC5863038 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Peng Hui H Zhang Yixiang Y Palmer Lauren D LD Kehl-Fie Thomas E TE Skaar Eric P EP Trinidad Jonathan C JC Giedroc David P DP
ACS infectious diseases 20170906 10
Hydrogen sulfide (H<sub>2</sub>S) is thought to protect bacteria from oxidative stress, but a comprehensive understanding of its function in bacteria is largely unexplored. In this study, we show that the human pathogen Staphylococcus aureus (S. aureus) harbors significant effector molecules of H<sub>2</sub>S signaling, reactive sulfur species (RSS), as low molecular weight persulfides of bacillithiol, coenzyme A, and cysteine, and significant inorganic polysulfide species. We find that proteome ...[more]