Ontology highlight
ABSTRACT:
SUBMITTER: Borello U
PROVIDER: S-EPMC5863514 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Borello Ugo U Berarducci Barbara B Delahaye Edwige E Price David J DJ Dehay Colette C
Frontiers in neuroscience 20180302
Multiple signals control the balance between proliferation and differentiation of neural progenitor cells during corticogenesis. A key point of this regulation is the control of G1 phase length, which is regulated by the Cyclin/Cdks complexes. Using genome-wide chromatin immunoprecipitation assay and mouse genetics, we have explored the transcriptional regulation of <i>Cyclin D1</i> (<i>Ccnd1</i>) during the early developmental stages of the mouse cerebral cortex. We found evidence that SP8 bind ...[more]