Ontology highlight
ABSTRACT:
SUBMITTER: Inoshita T
PROVIDER: S-EPMC5871328 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Inoshita Takuma T Hirano Tomoo T
eLife 20180327
Long-term depression (LTD) at parallel fiber (PF) to Purkinje cell (PC) synapses has been considered as a main cellular mechanism for motor learning. However, the necessity of LTD for motor learning was challenged by demonstration of normal motor learning in the LTD-defective animals. Here, we addressed possible involvement of LTD in motor learning by examining whether LTD occurs during motor learning in the wild-type mice. As a model of motor learning, adaptation of optokinetic response (OKR) w ...[more]