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IMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation.


ABSTRACT: We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14?000 genes) data for CD4+ T-lymphocytes, monocytes, and neutrophils collected from approximately 100 subjects. These data were obtained from whole-genome bisulfite sequencing, whole-genome sequencing, and whole-transcriptome sequencing, making iMETHYL a comprehensive database.

SUBMITTER: Komaki S 

PROVIDER: S-EPMC5874393 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation.

Komaki Shohei S   Shiwa Yuh Y   Furukawa Ryohei R   Hachiya Tsuyoshi T   Ohmomo Hideki H   Otomo Ryo R   Satoh Mamoru M   Hitomi Jiro J   Sobue Kenji K   Sasaki Makoto M   Shimizu Atsushi A  

Human genome variation 20180329


We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14 000 genes) data for CD4<sup>+</sup> T-lymphocytes, monocytes, and neutrophils collected from approximately 100 subjects. These data were obtained from whole-genome bisulfite sequencing, whole-genome sequencing, and whole-transcriptome sequencing, ma  ...[more]

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