Ontology highlight
ABSTRACT:
SUBMITTER: Jiang K
PROVIDER: S-EPMC5876081 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Jiang Kai K Tang Hui H Mishra Prasanna K PK Macura Slobodan I SI Lerman Lilach O LO
Magnetic resonance in medicine 20171128 1
<h4>Purpose</h4>Dynamic manganese-enhanced MRI (MEMRI) allows assessment of tissue viability by tracing manganese uptake. We aimed to develop a rapid T<sub>1</sub> mapping method for dynamic MEMRI to facilitate assessments of murine kidney viability.<h4>Methods</h4>A multi-slice saturation recovery fast spin echo (MSRFSE) was developed, validated, and subsequently applied in dynamic MEMRI at 16.4T on ischemic mouse kidneys after 4 weeks of unilateral renal artery stenosis (RAS). Baseline T<sub>1 ...[more]