Ontology highlight
ABSTRACT:
SUBMITTER: Busby M
PROVIDER: S-EPMC5877554 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Busby Mélanie M Hallett Michael T MT Plante Isabelle I
International journal of molecular sciences 20180228 3
Gap junction transmembrane channels allow the transfer of small molecules between the cytoplasm of adjacent cells. They are formed by proteins named connexins (Cxs) that have long been considered as a tumor suppressor. This widespread view has been challenged by recent studies suggesting that the role of Connexin 43 (Cx43) in cancer is tissue- and stage-specific and can even promote tumor progression. High throughput profiling of invasive breast cancer has allowed for the construction of subtypi ...[more]