Ontology highlight
ABSTRACT:
SUBMITTER: Cha JA
PROVIDER: S-EPMC5877726 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Cha Jin Ah JA Song Hyo-Sook HS Kang Beomku B Park Moon Nyeo MN Park Kyoung Sun KS Kim Sung-Hoon SH Shim Bum-Sang BS Kim Bonglee B
International journal of molecular sciences 20180315 3
Though <i>Cnidium officinale</i> Makino (COM) was known to have anti-angiogenic, anti-oxidant, neuroprotective, and anti-cancer effects, the underlying anticancer mechanism of COM using endoplasmic reticulum (ER) stress and miRNA remained unclear until now. Thus, in the current study, the inhibitory mechanism of COM in lymphoma and multiple myeloma (MM) cells was elucidated. COM exerted cytotoxicity in U937 and U266 but not Raw264.7 cells. COM treatment increased the expression of ER stress-rela ...[more]