Ontology highlight
ABSTRACT:
SUBMITTER: Liu W
PROVIDER: S-EPMC5879613 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Liu Weiwei W Wang Xuchu X Wang Yiyun Y Dai Yibei Y Xie Yiyi Y Ping Ying Y Yin Binbin B Yu Pan P Liu Zhenping Z Duan Xiuzhi X Liao Zhaoping Z Chen Yuhua Y Liu Chunhua C Li Xiang X Tao Zhihua Z
Journal of experimental & clinical cancer research : CR 20180402 1
<h4>Background</h4>Despite SGK1 has been identified and characterized as a tumor-promoting gene, the functions and underlying mechanisms of SGK1 involved in metastasis regulation have not yet been investigated in cancer.<h4>Methods</h4>We investigated the cellular responses to GSK650394 treatment and SGK1 silencing (or overexpression) in human prostate cancer (PCa) cell lines and PC3 xenografts by wound healing assay, migration and invasion assay, western blotting, immunofluorescence and immunoh ...[more]