KIF18B promotes tumor progression through activating the Wnt/?-catenin pathway in cervical cancer.
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ABSTRACT:
SUBMITTER: Wu Y
PROVIDER: S-EPMC5880519 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
KIF18B promotes tumor progression through activating the Wnt/β-catenin pathway in cervical cancer.
Wu Yaqin Y Wang Anpeng A Zhu Biqing B Huang Jian J Lu Emei E Xu Hanzi H Xia Wenjie W Dong Gaochao G Jiang Feng F Xu Lin L
OncoTargets and therapy 20180328
<h4>Background</h4>KIF18B was identified as a potential oncogene by analysis of The Cancer Genome Atlas database.<h4>Materials and methods</h4>We assessed KIF18B expression and explored its clinical significance in cervical cancer tissues. We have also evaluated the effects of KIF18B on cervical cancer cell proliferation, migration, and invasion both in vitro and in vivo.<h4>Results</h4>Our results show that KIF18B is overexpressed in cervical cancer tissues and is associated with a large primar ...[more]
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