Ontology highlight
ABSTRACT:
SUBMITTER: Suksawat M
PROVIDER: S-EPMC5881549 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Suksawat Manida M Techasen Anchalee A Namwat Nisana N Boonsong Thianrut T Titapun Attapol A Ungarreevittaya Piti P Yongvanit Puangrat P Loilome Watcharin W
FEBS open bio 20180302 4
The isoform of nitric oxide synthase (NOS) found in endothelial cells (eNOS) plays a crucial role in vasodilation. We recently reported the activation of eNOS in cholangiocarcinoma (CCA) tissues and cell lines. Moreover, we also reported that the abundance of eNOS and phosphorylated eNOS (p-eNOS), as well as its upstream regulator proteins, is significantly associated with the metastatic status of CCA patients. However, the function of eNOS in CCA progression has not been addressed. Therefore, t ...[more]