Ontology highlight
ABSTRACT:
SUBMITTER: Knott EJ
PROVIDER: S-EPMC5882642 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Knott Eric J EJ Gordon William C WC Jun Bokkyoo B Do Khanh K Bazan Nicolas G NG
Cellular and molecular neurobiology 20171124 4
Omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) are necessary for functional cell integrity. Preconditioning (PC), as we define it, is an acquired protection or resilience by a cell, tissue, or organ to a lethal stimulus enabled by a previous sublethal stressor or stimulus. In this study, we provide evidence that the omega-3 fatty acid docosahexaenoic acid (DHA) and its derivatives, the docosanoids 17-hydroxy docosahexaenoic acid (17-HDHA) and neuroprotectin D1 (NPD1), facilitate cell su ...[more]