Ontology highlight
ABSTRACT:
SUBMITTER: Tsinias G
PROVIDER: S-EPMC5884441 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Tsinias Georgios G Nikou Sofia S Papadas Theodoros T Pitsos Panagiotis P Papadaki Helen H Bravou Vasiliki V
Analytical cellular pathology (Amsterdam) 20180320
Focal adhesion signaling to actin cytoskeleton is critically implicated in cell migration and cancer invasion and metastasis. Actin-binding proteins cofilin and N-WASP regulate actin filament turnover, and focal adhesion proteins parvins and PINCH mediate integrin signaling to the actin cytoskeleton. Altered expression of these proteins has been implicated in human cancer. This study addresses their expression and prognostic significance in human laryngeal carcinoma. Protein expressions of cofil ...[more]