High c-Myb Expression Associates with Good Prognosis in Colorectal Carcinoma.
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ABSTRACT:
SUBMITTER: Tichy M
PROVIDER: S-EPMC6485226 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
High c-Myb Expression Associates with Good Prognosis in Colorectal Carcinoma.
Tichý Michal M Knopfová Lucia L Jarkovský Jiří J Vlček Petr P Katolická Jana J Čapov Ivan I Hermanová Markéta M Šmarda Jan J Beneš Petr P
Journal of Cancer 20190223 6
Colorectal cancer (CRC) represents a serious challenge for oncologists due to high incidence and large heterogeneity. Prognostic factors are needed to stratify patients according to risk of disease progression. In this study, we report that high expression of c-Myb protein, determined by immunohistochemistry (IHC), associates with better overall and disease-free survival (OS, DFS) in a cohort of 103 patients. Although <i>MYB</i> has been previously considered to act as oncogene in CRC, our furth ...[more]
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