Ontology highlight
ABSTRACT:
SUBMITTER: Nimmervoll BV
PROVIDER: S-EPMC5884708 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Nimmervoll Birgit V BV Boulos Nidal N Bianski Brandon B Dapper Jason J DeCuypere Michael M Shelat Anang A Terranova Sabrina S Terhune Hope E HE Gajjar Amar A Patel Yogesh T YT Freeman Burgess B BB Onar-Thomas Arzu A Stewart Clinton F CF Roussel Martine F MF Guy R Kipling RK Merchant Thomas E TE Calabrese Christopher C Wright Karen D KD Gilbertson Richard J RJ
Clinical cancer research : an official journal of the American Association for Cancer Research 20180104 7
<b>Purpose:</b> Curing all children with brain tumors will require an understanding of how each subtype responds to conventional treatments and how best to combine existing and novel therapies. It is extremely challenging to acquire this knowledge in the clinic alone, especially among patients with rare tumors. Therefore, we developed a preclinical brain tumor platform to test combinations of conventional and novel therapies in a manner that closely recapitulates clinic trials.<b>Experimental De ...[more]