Ontology highlight
ABSTRACT:
SUBMITTER: Freedman MS
PROVIDER: S-EPMC5891690 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Freedman Mark S MS Wolinsky Jerry S JS Comi Giancarlo G Kappos Ludwig L Olsson Tomas P TP Miller Aaron E AE Thangavelu Karthinathan K Benamor Myriam M Truffinet Philippe P O'Connor Paul W PW
Multiple sclerosis (Houndmills, Basingstoke, England) 20170317 4
Teriflunomide is a once-daily oral immunomodulator approved for relapsing-remitting multiple sclerosis (MS). The objective of this post hoc analysis of the phase 3, pooled TEMSO (NCT00134563) and TOWER (NCT00751881) dataset is to evaluate the effect of teriflunomide treatment on annualised relapse rate and disability worsening across patient subgroups defined according to prior disease-modifying therapy exposure. This analysis provides further supportive evidence for a consistent effect of terif ...[more]