Ontology highlight
ABSTRACT:
SUBMITTER: Friedman A
PROVIDER: S-EPMC5892900 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Friedman Avner A Siewe Nourridine N
PloS one 20180410 4
Hepatitis B virus (HBV) infection is a liver disorder that can result in cirrhosis, liver failure and hepatocellular carcinoma. HBV infection remains a major global health problem, as it affects more 350 million people chronically and kills roughly 600,000 people annually. Drugs currently used against HBV include IFN-α that decreases viremia, inflammation and the growth of liver fibrosis, and adefovir that decreases the viral load. Each of these drugs can have severe side-effects. In the present ...[more]