Ontology highlight
ABSTRACT:
SUBMITTER: Vahedi-Hunter TA
PROVIDER: S-EPMC5902548 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Vahedi-Hunter Tyler A TA Estep Jason A JA Rosette Kylee A KA Rutlin Michael L ML Wright Kevin M KM Riccomagno Martin M MM
Scientific reports 20180416 1
Development of complex neural circuits like the peripheral somatosensory system requires intricate mechanisms to ensure axons make proper connections. While much is known about ligand-receptor pairs required for dorsal root ganglion (DRG) axon guidance, very little is known about the cytoplasmic effectors that mediate cellular responses triggered by these guidance cues. Here we show that members of the Cas family of cytoplasmic signaling adaptors are highly phosphorylated in central projections ...[more]