Ontology highlight
ABSTRACT:
SUBMITTER: Suter TACS
PROVIDER: S-EPMC7049094 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Suter Tracey A C S TACS Blagburn Sara V SV Fisher Sophie E SE Anderson-Keightly Heather M HM D'Elia Kristen P KP Jaworski Alexander A
Cell reports 20200101 4
Neuronal migration, axon fasciculation, and axon guidance need to be closely coordinated for neural circuit assembly. Spinal motor neurons (MNs) face unique challenges during development because their cell bodies reside within the central nervous system (CNS) and their axons project to various targets in the body periphery. The molecular mechanisms that contain MN somata within the spinal cord while allowing their axons to exit the CNS and navigate to their final destinations remain incompletely ...[more]