Ontology highlight
ABSTRACT:
SUBMITTER: Ma S
PROVIDER: S-EPMC5906078 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Ma Sai S Hsieh Yuan-Pang YP Ma Jian J Lu Chang C
Science advances 20180418 4
Extensive effort is under way to survey the epigenomic landscape of primary ex vivo tissues to establish normal reference data and to discern variation associated with disease. The low abundance of some tissue types and the isolation procedure required to generate a homogenous cell population often yield a small quantity of cells for examination. This difficulty is further compounded by the need to profile a myriad of epigenetic marks. Thus, technologies that permit both ultralow input and high ...[more]