Quantifying the effect of uncertainty in input parameters in a simplified bidomain model of partial thickness ischaemia.
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ABSTRACT:
SUBMITTER: Johnston BM
PROVIDER: S-EPMC5906519 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Publications
Quantifying the effect of uncertainty in input parameters in a simplified bidomain model of partial thickness ischaemia.
Johnston Barbara M BM Coveney Sam S Chang Eugene T Y ETY Johnston Peter R PR Clayton Richard H RH
Medical & biological engineering & computing 20170920 5
Reduced blood flow in the coronary arteries can lead to damaged heart tissue (myocardial ischaemia). Although one method for detecting myocardial ischaemia involves changes in the ST segment of the electrocardiogram, the relationship between these changes and subendocardial ischaemia is not fully understood. In this study, we modelled ST-segment epicardial potentials in a slab model of cardiac ventricular tissue, with a central ischaemic region, using the bidomain model, which considers conducti ...[more]
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