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Association of maternal serum 25-hydroxyvitamin D concentrations in second and third trimester with risk of macrosomia.


ABSTRACT: Whether the maternal vitamin D deficiency is associated with infant birth weight is still an argument. Here, we performed a nested case-control study (545 women who subsequently delivered infant with macrosomia and 1090 controls) to evaluate the association of the maternal serum 25-hydroxyvitamin D [25(OH)D] concentrations with risk of macrosomia. We measured the serum 25(OH)D concentrations by enzyme immunoassays. Logistic regression analysis, receiver-operator characteristic curve analysis and graphical nomogram were used for the statistical analyses. Among women who delivered infant with macrosomia, 71.2% of the women had serum 25(OH)D concentrations <50.0 nmol/L compared with 61.1% of the control women (P?

SUBMITTER: Wen J 

PROVIDER: S-EPMC5906563 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Association of maternal serum 25-hydroxyvitamin D concentrations in second and third trimester with risk of macrosomia.

Wen Juan J   Kang Congli C   Wang Jiaan J   Cui Xianwei X   Hong Qin Q   Wang Xingyun X   Zhu Lijun L   Xu Pengfei P   Fu Ziyi Z   You Lianghui L   Wang Xing X   Ji Chenbo C   Guo Xirong X  

Scientific reports 20180418 1


Whether the maternal vitamin D deficiency is associated with infant birth weight is still an argument. Here, we performed a nested case-control study (545 women who subsequently delivered infant with macrosomia and 1090 controls) to evaluate the association of the maternal serum 25-hydroxyvitamin D [25(OH)D] concentrations with risk of macrosomia. We measured the serum 25(OH)D concentrations by enzyme immunoassays. Logistic regression analysis, receiver-operator characteristic curve analysis and  ...[more]

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