Ontology highlight
ABSTRACT:
SUBMITTER: Yan L
PROVIDER: S-EPMC5908115 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Yan Lihua L Wu Xiangkun X Yin Xianzhe X Du Feng F Liu Yongxi Y Ding Xunmeng X
Journal of cellular and molecular medicine 20180304 5
Long non-coding RNA (lncRNA) plays important roles in tumour progression. Accumulating studies demonstrated that lncRNA colon cancer-associated transcript 2 (CCAT2) acted as an oncogene in many tumours. However, the role of CCAT2 in the development of osteosarcoma has not been elucidated. In our study, we indicated that CCAT2 expression was up-regulated in osteosarcoma tissues and cell lines (SOSP-9607, MG-63, U2OS and SAOS-2). In addition, osteosarcoma cases with higher CCAT2 expression had a p ...[more]