Clinicopathological significance of cystatin A expression in progression of esophageal squamous cell carcinoma.
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ABSTRACT:
SUBMITTER: Shiba D
PROVIDER: S-EPMC5908574 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Publications
Clinicopathological significance of cystatin A expression in progression of esophageal squamous cell carcinoma.
Shiba Daiki D Terayama Masayoshi M Yamada Kazuhiko K Hagiwara Teruki T Oyama Chinatsu C Tamura-Nakano Miwa M Igari Toru T Yokoi Chizu C Soma Daisuke D Nohara Kyoko K Yamashita Satoshi S Dohi Taeko T Kawamura Yuki I YI
Medicine 20180401 15
We previously conducted transcriptome analysis of a paired specimen of normal and esophageal squamous cell carcinoma (ESCC) tissues and found that mRNA expression of cystatin A (CSTA), a member of the cystatin superfamily, was perturbed in tumors compared with that in the background mucosa. However, little is known about the significance of CSTA expression in ESCC.The mRNA expression of CSTA was evaluated by qRT-PCR using 28 paired frozen samples of tumor and nontumor mucosae. The protein expres ...[more]
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