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Post-study caffeine administration enhances memory consolidation in humans.


ABSTRACT: It is currently not known whether caffeine has an enhancing effect on long-term memory in humans. We used post-study caffeine administration to test its effect on memory consolidation using a behavioral discrimination task. Caffeine enhanced performance 24 h after administration according to an inverted U-shaped dose-response curve; this effect was specific to consolidation and not retrieval. We conclude that caffeine enhanced consolidation of long-term memories in humans.

SUBMITTER: Borota D 

PROVIDER: S-EPMC5909971 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature

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Post-study caffeine administration enhances memory consolidation in humans.

Borota Daniel D   Murray Elizabeth E   Keceli Gizem G   Chang Allen A   Watabe Joseph M JM   Ly Maria M   Toscano John P JP   Yassa Michael A MA  

Nature neuroscience 20140112 2


It is currently not known whether caffeine has an enhancing effect on long-term memory in humans. We used post-study caffeine administration to test its effect on memory consolidation using a behavioral discrimination task. Caffeine enhanced performance 24 h after administration according to an inverted U-shaped dose-response curve; this effect was specific to consolidation and not retrieval. We conclude that caffeine enhanced consolidation of long-term memories in humans. ...[more]

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