Circulating microRNAs as potential cancer biomarkers: the advantage and disadvantage.
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ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC5913875 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Circulating microRNAs as potential cancer biomarkers: the advantage and disadvantage.
Wang Hao H Peng Ran R Wang Junjie J Qin Zelian Z Xue Lixiang L
Clinical epigenetics 20180423
MicroRNAs are endogenous single-stranded non-coding small RNA molecules that can be secreted into the circulation and exist stably. They usually exhibit aberrant expression under different physiological and pathological conditions. Recently, differentially expressed circulating microRNAs were focused on as potential biomarkers for cancer screening. We herein review the role of circulating microRNAs for cancer diagnosis, tumor subtype classification, chemo- or radio-resistance monitoring, and out ...[more]
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