Ontology highlight
ABSTRACT:
SUBMITTER: Wang D
PROVIDER: S-EPMC5918528 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Wang Dandan D Zhang Huayong H Liang Jun J Wang Hong H Hua Bingzhu B Feng Xuebing X Gilkeson Gary S GS Farge Dominique D Shi Songtao S Sun Lingyun L
Stem cell reports 20180301 3
Allogeneic mesenchymal stem/stromal cells (MSCs) have been widely studied as an alternative cell source for regenerative medicine. Here, we report a long-term follow-up study of allogeneic bone marrow and/or umbilical cord MSC transplantation (MSCT) in severe and drug-refractory systemic lupus erythematosus (SLE) patients. Eighty-one patients were enrolled, and the 5-year overall survival rate was 84% (68/81) after MSCT. At 5-year follow-up, 27% of patients (22/81) were in complete clinical remi ...[more]