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Enhanced JBrowse plugins for epigenomics data visualization.

ABSTRACT:

Background

New sequencing techniques require new visualization strategies, as is the case for epigenomics data such as DNA base modifications, small non-coding RNAs, and histone modifications.

Results

We present a set of plugins for the genome browser JBrowse that are targeted for epigenomics visualizations. Specifically, we have focused on visualizing DNA base modifications, small non-coding RNAs, stranded read coverage, and sequence motif density. Additionally, we present several plugins for improved user experience such as configurable, high-quality screenshots.

Conclusions

In visualizing epigenomics with traditional genomics data, we see these plugins improving scientific communication and leading to discoveries within the field of epigenomics.

SUBMITTER: Hofmeister BT

PROVIDER: S-EPMC5921565 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Enhanced JBrowse plugins for epigenomics data visualization.

Hofmeister Brigitte T BT Schmitz Robert J RJ

BMC bioinformatics 20180425 1

<h4>Background</h4>New sequencing techniques require new visualization strategies, as is the case for epigenomics data such as DNA base modifications, small non-coding RNAs, and histone modifications.<h4>Results</h4>We present a set of plugins for the genome browser JBrowse that are targeted for epigenomics visualizations. Specifically, we have focused on visualizing DNA base modifications, small non-coding RNAs, stranded read coverage, and sequence motif density. Additionally, we present severa ...[more]

PMID: 29699480

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